It doesn't matter what city works what tile, as long as you work them all - for as long as possible. What you need to concern yourself with is working all the good tiles inside your borders. If you wanna get any use of those tiles you need to have several other cities near by!

You don't need to play Civ to know that the more an empire expands its borders and has more territory to defend. Also note that a few Food resources enables you to run several specialists in a city, resulting in the rest of the tiles around the city not being worked. wide: The more cities you own in Civ 6, the more deadly wars can become. I usually try for 3 to 6 tiles between cities, but sometimes you need to put a city. Unless you grow really large cities it is unlikely you will be able to work tiles outside the third ring, but you could still hook up resources further out than 3 rings when your culture borders expand that far. So the distance between cities could be anything from 2 to 10 tiles, depending on the circumstances. Three tiles apart is the minimum distance. Building any other city in that entire region would just be a strain to your economy. But if all you have is Plains or Desert or Tundra - and endless coastlines with no seafood resources - then you may only need one city to harvest what ever special resource that is present. This means that if you have lots of Grasslands, Rivers and Forested Hills - along with too many special resources for a single city to work effectively - then you can fit in more cities in that terrain. Make sure that every city has some good tiles to work. In practice, you should settle 4-5 hexes apart to maximize the number of cities. Yet another way of planning city placement: Base it on the terrain. To answer your question, your city can work tiles three hexes from the city centre, so if you want to maximize territory you need to settle 6 hexes apart.

Civ 6 how far apart cities